Hyaluronan Your Skins Best Friend!

What is it?

Hyaluronan (also called hyaluronic acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions. One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration.

Properties of hyaluronan were first determined in the 1930s in the laboratory of Karl Meyer.

Hyaluronic acid is naturally found in a multitude of tissues throughout our body such as skin and cartilage, according to the National Institutes of Health. It is needed for wound healing, cartilage and joint functioning, pain management, tissue repair and skin regeneration. There are a plethora of foods you can eat that are rich in this needed acid.

It is a substance which aging bodies typically lose over time. Ingesting supplements containing Hyal-Joint (NIH studies have proven the effectiveness) and foods containing high levels may ward off the aging process by helping the cells of the body thrive and retain moisture, keeping joints lubricated, protecting the retina in eyes and keeping skin smooth and elastic.

Hyal-Joint® is a unique natural product with a high content of sodium hyaluronate, the chief component of synovial fluid. It also contains collagen, the main protein present in joints and the key to flexible, strong tissue, as well as other glycosaminoglycans, which also play an important role in joint performance. Hyal-Joint® supplementation helps keep hyaluronic acid concentrations within a healthy range, thereby promoting comfortable joint mobility and reducing stiffness. Hyal-Joint is 2 to 4 times more active in nourishing synovial fluid and supporting its health than regular hyaluronic acid. The Author is not affilated with Hyal-Joint in any way.


Satsumaimo, a type of sweet potato

Satoimo, a sticky white potato

Konyaku, a gelatinous root vegetable concoction

Imoji, a potato root

Root vegetables do tend to have high amounts of magnesium which work with hyaluronic acid to repair & maintain collagen.

Beans & some legumes (soy anyone?)

Cocks coombs

Foods with skin, tendons and joints

Foods high in retinol, a component of vitamin A, will contain high amounts of hyaluronic acid, according to a 2008 study conducted by Gary J. Fischer, PhD (Professor of Dermatology) of the University of Michigan Health Systems. The study, cited in the Archives of Dermatology, claims that a cross-linked blend of hyaluronic and retonic acid is beneficial to skin healing and collagen regeneration due to their vitamin A antioxidant properties.

According to nutritiondata.com, a variety of organ meats are high in retinol. Organ meats include gizzards, livers, hearts and kidneys. Raw and cooked versions are both high in the component. Veal, lamb, beef, turkey, goose, duck and turkey are all rich sources. As an example, a 1-ounce serving of cooked turkey liver will supply you with 6,300mcg of retinol, which is the equivalent of 422 percent of your daily recommended allotment of retinol and vitamin A. Cod liver oil contains a high amount of vitamin A and retinol, according to the USDA. Nutritiondata.com says that a 1-ounce serving of fish cod liver oil contains 8,400mcg of vitamin A and retinol. This is the equivalent of supplying you with 560 percent of your daily recommended allotment of the vitamin.

FYI: vitamin C helps you make the collagen that keeps skin firm. And regular exfolation stimulates hyaluronic acid.

Yuzurihara Diet

Skin provides a barrier to the external environment and acts to prevent  infectious agents from entering the body.Once injured, the tissues beneath are exposed to infection; therefore, rapid and effective healing is of crucial significance to reconstruct a barrier function. Skin wound healing is a complex process, and includes many interacting processes initiated by haemostasis and the release of platelet-derived factors. The following stages are inflammation, granulation tissue formation, reepithelization and remodeling. Hyaluronic Acid is most likely to be instrumental in these cellular and matrix events.

Although inflammation is an integral part of granulation tissue formation, for normal tissue repair to proceed, inflammation needs to be moderated.  Hyaluronic Acid can protect against free-radical damage to cells. This may attribute to its free-radical scavenging property.

Hyaluronic Acid content increases at the presence of retinoic acid (vitamin A). The proposed effects of retinoic acid against skin photo-damage and aging may be correlated, at least in part, with an increase of skin Hyaluronic Acid content, giving rise to increase of tissue hydration. It has been suggested the free-radical scavenging property of Hyaluronic Acid contributes to protection against solar radiation. High concentrations of hyaluronan in the brains of young rats, and reduced concentrations in the brains of adult rats suggest hyaluronan plays an important role in brain development.

How much does my body have?

The average 70 kg (154 lb) person has roughly 15 grams of hyaluronan in the body, one-third of which is turned over (degraded and synthesized).


Hyaluronan has been used in attempts to treat osteoarthritis of the knee via injecting it into the joint.

Dry, scaly skin (xerosis) such as that caused by atopic dermatitis (eczema) may be treated with a prescription skin lotion containing sodium hyaluronate as its active ingredient.

Hyaluronan may also be used postoperatively to induce tissue healing, notably after cataract surgery. Current models of wound healing propose the larger polymers of hyaluronic acid appear in the early stages of healing to physically make room for white blood cells, which mediate the immune response.

Hyaluronan has also been used in the synthesis of biological scaffolds for wound-healing applications. These scaffolds typically have proteins such as fibronectin attached to the hyaluronan to facilitate cell migration into the wound. This is particularly important for individuals with diabetes suffering from chronic wounds.

Eye surgeons use hyaluronic acid to supplement natural fluids during surgeries, including corneal transplants, cataract removal, retina repair and other procedures.

Cosmetic surgeons use hyaluronic acid as fillers in various plastic surgical procedures. Scientists at the University of Maryland School of Medicine in Baltimore, Maryland report more than 85 percent of dermal filler procedures involve the use of hyaluronic acid, according to research published in “Facial Plastic Surgery” in May 2009.

You can also use hyaluronic acid to moisturize the skin and help heal burns, wounds and ulcers it is found in many skin care products.

Visco-elastic properties it reduces friction between cartilage surfaces.

via Hyal-Joint

via Hyal-Joint

Metabolic properties in Homeostasis of the synovial fluid.

Look for supplements from natural resources , not fermented products which are synthesized by biotechnology using a genetically modified organism. The impurities profile is different and also the molecular weight (typically fermented AH has a much higher molecular weight).

While I’ve attempted to use
credible sources for information, this is not intended to be a substitute for professional medical advice or treatment. If there is a disparity between the information presented within this blog and the advice given by your medical professional, please follow the medical professional’s
advice as he/she will know you
and your medical circumstances.


  1. Here is a nice article http://www.skincancer.org/news/tanning/study-finds-sunless-tanning-deters-uv-tanning
    You’re right about the glow

    I’ve noticed with self tanner on the face you can sometimes get very small orange dots where the tanner settled in your pores especially the nose where pores tend to be larger

    Self tanner like in the article really does help people for tanning less which good for their over all health



  1. […] my article on Hyaluronic Acid for health & skin […]


  2. […] from hyaluronic acid production. Hyaluronic acid is naturally found in a multitude of tissues throughout our body such […]


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